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filingDate 2013-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015533504-A
titleOfInvention Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis
abstract By removing mucus from the intracervical sample by separating fetal cells and maternal cells in the intracervical sample, and isolating the separated fetal cells from other cells in the intracervical sample A method for recovering fetal cells from a sample in the cervix is provided. By obtaining a mixture of isolated cells prepared by the above method, treating the cells with a fetal-specific antibody, identifying cells bound to the fetal-specific antibody, and isolating the identified cells, A method for recovering fetal cells from an intracervical sample is also provided. The isolated cells prepared by the above method can be analyzed and used for various applications, including identification of fetal cells from cervical cells, fetal cell density to predict high risk pregnancy Determination, genetic analysis of fetal cells, and measurement of expression of growth factors and other biomarkers to predict obstetrical disorders.
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