| abstract |
The present invention relates to a method for producing a purified gold and silver flower extract and a composition for preventing and treating sepsis and septic shock including the same. The purified gold and silver flower extract according to the present invention is used in terms of severe sepsis CLP model test, influence on MODS, and inhibitory effect of various inflammatory cytokines such as TNF-α, IL-1β, IFN-γ, and HMGB-1. It exhibits potent anti-septic activity and, when used with a commercially available anti-septic agent such as a broad spectrum antibiotic, shows an unexpected synergistic effect in the treatment of sepsis and septic shock, and is used as a pharmaceutical and health functional food. And can be used effectively for the treatment and prevention of septic shock. [Selection] Figure 2 |