| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10152 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
| filingDate |
2013-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2015528291-A |
| titleOfInvention |
Methods and compositions for producing cells having a phenotype of primary human hepatocytes |
| abstract |
The present disclosure provides methods and compositions relating to in vitro cultures of human hepatocyte cell lines exhibiting a primary human hepatocyte phenotype. Such cell lines are susceptible to infection by hepatic viruses such as HCV or HBV and support both viral replication and high levels of viral particle production. Such in vitro cultures find use in the production and research of hepatic viruses and methods of screening (eg, for antiviral drugs, to assess drug metabolism) and in the study of primary human hepatocytes. . [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017110931-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017110931-A1 |
| priorityDate |
2012-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |