http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015523879-A

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filingDate 2013-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015523879-A
titleOfInvention Improved syringe
abstract A syringe that can be propelled by a propellant that boils at a predetermined temperature, and includes a barrel having an outlet at a front end and a stopper that is axially movable within the barrel. The stopper defines a first chamber and a second chamber and is separated from each other, the first chamber being positioned axially forward of the stopper and configured to contain a medicament. The second chamber is located axially rearward of the stopper, accepts a propellant for acting on the stopper when the syringe is activated, moves the stopper axially forward in the barrel, and discharges the drug Configured to release through. The syringe further comprises a third chamber for containing the breach and the propellant, the third chamber being ruptureable. The breaching portion ruptures the third chamber upon actuation of the syringe, fluidly connects the third chamber to the second chamber, and releases liquid propellant from the third chamber, thereby causing the second chamber to Is increased at a predetermined temperature or at a temperature exceeding the predetermined temperature, and the stopper is moved axially forward to release the drug from the first chamber through the outlet. When the propellant is released into the second chamber, the pressure in the second chamber increases to the first pressure over a first time interval, moving the stopper axially forward and causing the drug to move to the first chamber. It begins to discharge from the chamber through the outlet. The syringe is configured such that the pressure in the second chamber changes from the first pressure to the second pressure over a second time interval while the drug is released from the first chamber. When substantially all of the drug is released from the first chamber, the pressure in the second chamber increases toward the third pressure over a third time interval. The magnitude of the second pressure and the rate of increase in pressure in the second chamber during the third time interval is determined by the heat transfer rate of the components of the syringe defining the second chamber, to the second chamber. Controlled by the rate of propellant delivery and the phase of the propellant being delivered into the second chamber. The third pressure is substantially equal to the vapor pressure of the propellant at an ambient temperature of the instantaneous volume of evaporated propellant, at which the syringe contains a liquid propellant.
priorityDate 2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419546554
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Total number of triples: 37.