| abstract |
The present invention provides chromatographic stationary phase materials for a variety of different types of chromatography. An example of a chromatography stationary phase is represented by Formula 1 [X] (W) a (Q) b (T) c (Formula 1). X may be a high purity chromatography core composition. W may be absent and / or may contain hydrogen and / or may contain hydroxyl on the surface of X. Q may be directly attached to X and may comprise a first hydrophilic, polar, ionic and / or charged functional group that interacts chromatographically with the analyte. T may be directly attached to X and may include a second hydrophilic, polar, ionic and / or charged functional group that interacts chromatographically with the analyte. In addition, Q and T essentially eliminate the chromatographic interaction between the analyte and X and W, so that variation in retention over time (drift or drift) under chromatographic conditions using low water concentrations. Change) can be minimized. |