| abstract |
The present invention relates to a compound of formula (I): [Where: X is NH or O; Q is substituted by one or more substituents independently selected from the group consisting of C1-C4 alkyl, halogen, halo C1-C4 alkyl, C1-C4 alkoxy, CN Is a 5-6 membered heteroaryl group; A is one or more independently selected from the group consisting of C1-C4 alkyl, halogen, halo C1-C4 alkyl, C1-C4 alkoxy, CN A phenyl or a 5-6 membered heteroaryl group optionally substituted by a substituent of B; B may have a meaning different from A; C1-C4 alkyl, halogen, halo C1-C4 alkyl , C1-C4 alkoxy, optionally substituted by one or more substituents independently selected from the group consisting of CN, phenyl or 5 A heteroaryl group membered 6] Or a stereoisomer, racemate or mixture thereof, or a pharmaceutically acceptable salt thereof; and a method for producing the same, a pharmaceutical composition containing them, and their orexin-1 and orexin-2 receptors For use as a dual antagonist. |