| abstract |
The present invention is an aqueous pharmaceutical composition comprising an ionized therapeutic agent, an ionic component, and guar gum. Guar gum is present in the composition at a concentration sufficient to limit the interaction between the ionized therapeutic agent and the ionic component, thereby providing stability to the composition. The composition is preferably at or near physiological pH. Aqueous pharmaceutical compositions have been found to be particularly useful as aqueous ophthalmic, ear or nasal compositions. The pharmaceutical composition is particularly suitable as an ophthalmic composition because of its properties. [Selection figure] None |