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filingDate 2013-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015509598-A
titleOfInvention Multiplex chromatography-immunoassay method for characterizing circulating immune complexes
abstract Thus, herein, size exclusion chromatography of a sample obtained from a mammal to which the drug has been administered at least once to determine the weight / size of the immune complex, and possibly not a second SEC A method for analyzing / characterizing circulating immune complexes (CIC) formed in vivo, including chromatography and at least one immunoassay, has been reported, wherein the immune complexes are determined by the size of the immune complex and the immunoassay. Of the results / correlation with readings. Also, as used herein, immune response and hypersensitivity for measuring neutralization of a drug's natural counterpart, for measuring loss of potency or reduction, for measuring correlation with changes in pharmacokinetics The use of the methods reported herein for measuring responses (including diseases mediated by serum sickness / type III hypersensitivity reactions / immune complexes) has been reported.
priorityDate 2012-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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