abstract |
The present invention provides, among other aspects, a method for producing a blood protein composition from stored plasma. In one embodiment, the present invention provides an alcohol fractionation scheme that allows a significant increase in the yield of blood protein purified from the starting plasma sample. In certain specific embodiments, a method of fractionating stored plasma is provided, the method comprising an initial low pH, high alcohol precipitation step. The present invention also provides pharmaceutical compositions of therapeutic blood proteins. |