| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-952
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-14003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2013-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2015-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2015509372-A |
| titleOfInvention |
Means and methods for measuring neurotoxic activity based on modified luciferase |
| abstract |
The present invention relates to a test system for measuring the activity of a neurotoxin polypeptide. Specifically, the present invention provides (i) a LuxB subunit, (ii) a linker containing a neurotoxin cleavage site, and (iii) a polynucleotide encoding a single-stranded luciferase fusion polypeptide comprising a LuxA subunit and the above And the polypeptide encoded by the polynucleotide. The present invention further provides vectors and host cells comprising the above polynucleotides. Furthermore, the present invention relates to a method for measuring a neurotoxin polypeptide having proteolytic activity in a sample and a kit for carrying out this method. [Selection] Figure 1 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101981199-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017204561-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170132697-A |
| priorityDate |
2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |