abstract |
The present invention relates to the following formula (I) [Chemical 1] I Compounds, their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing them, and neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, such as dementia Alternatively, it relates to a method for using them as a therapeutic and / or prophylactic agent for cognitive impairment. A, B, Ar, R 1 , R 2 and R 3 have the meanings described in the specification. [Selection figure] None |