| abstract |
The present invention provides compounds of Formula IB: (IB), wherein HY, R 1 , R 2 , R 3 , R 15 , G 5 , G 6 , G 7 , G 8 , and G 9 are As described herein. These compounds are inhibitors of VPS34 and / or PI3K and are therefore useful for the treatment of proliferative, inflammatory, or cardiovascular disorders. Wherein, -G 5 -G 6 -G 7 -G 8 -G 9 are, -CR 3 = C-N- N = C, = N-N-C = CR 3 -C, = CR 3 -C = C—NR 15 —C, —CR 3 = C—N—CR 3 = C, = CR 3 —N—C = CR 3 —C, or —NR 15 —C = C—CR 3 = C. [Selection figure] None |