http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015502959-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2015502959-A |
| titleOfInvention | Separation of IgG2 disulfide isoform |
| abstract | Disclosed is a method for producing an IgG2 antibody formulation enriched in one of several IgG2 structural isoforms that differ by disulfide bonds in the hinge region of the antibody. For example, a method of generating an IgG2 antibody formulation enriched in one of several IgG2 structural isoforms that differ by disulfide bonds in the hinge region of the antibody, having a kappa light chain of the VκI, VκIII, or VκIV subclass There is provided a method comprising subjecting a formulation comprising an IgG2 antibody to a protein L resin, wherein the IgG2 antibody in the formulation is eluted from the protein L resin as two or more structural IgG2 isoforms. [Selection] Figure 16 |
| priorityDate | 2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.