| abstract |
The present invention provides a method comprising combination therapy for treating cancer. Specifically, the present invention provides Wnt pathway inhibitors in combination with MAPK pathway inhibitors for the treatment of cancer and other diseases. In some embodiments, MAPK pathway signaling activation is due to mutations in MAPK pathway components. In some embodiments, the MAPK pathway signaling component is Ras, Raf, MEK, or ERK. |