abstract |
Occurs caused by or associated with the production of toxic visual cycle products that accumulate in the eye, such as dry adult macular disease, and caused by misfolding of mutant opsin proteins and / or mislocalization of opsin proteins Disclosed are compounds and compositions useful for treating symptoms associated with. Therapeutic methods using such compounds and / or compositions together with compositions of these compounds alone or in combination with another therapeutic agent are disclosed. Also disclosed are methods for synthesizing such agents. |