Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 |
filingDate |
2015-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_423c426a5a2bef8da1777645c0050aca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eac5a997378f2c30f78bf75884d15779 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_067687fc00a02f7f68e76f0cd1e3a8eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b3fc17b0df186a2368f295ba9fd127 |
publicationDate |
2015-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2015227376-A |
titleOfInvention |
Combination of pneumococcal RrgB clade |
abstract |
PROBLEM TO BE SOLVED: To provide a combination of Streptococcus pneumoniae RrgB clade. The pneumococcal pili subunit RrgB has at least three clades. Sera raised against a given clade is active against pneumococci expressing that RrgB clade, but not against strains expressing one of the other two clades. That is, there is an intra-clade cross defense, but no inter-craid cross defense. Thus, the immunogenic composition may comprise at least two different clades of RrgB to improve strain coverage against pili containing pneumococci. These multiple clades may be present as separate polypeptides or fused as a single polypeptide chain in the immunogenic composition. [Selection figure] None |
priorityDate |
2009-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |