http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015218129-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb2edb0f237a90d982f2dce09ad61976 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-29 |
filingDate | 2014-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b6267abbf2eccf2d289ff568680760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ffd8e5d54304be836eb39f45fd8d946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03439c5d10bea61148ff2147fd2f3e8d |
publicationDate | 2015-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2015218129-A |
titleOfInvention | 4-substituted-1-hydroxynaphthalene-2-sulfonamide-amine adduct and process for producing the same |
abstract | The present invention relates to a method for synthesizing a naphthalenesulfonamide compound used as a calmodulin inhibitor without naphthalenesulfonyl chloride, and the sulfonamide group is located at the 2-position of the naphthalene ring, and an electron atom such as an oxygen atom is substituted as a substituent. A novel 4-substituted-1-hydroxynaphthalene-2-sulfonamido-amine adduct having a functional substituent introduced therein. A 4-substituted-1-hydroxynaphthalene represented by the formula (1) in which 1,4-dihydroxynaphthalene-2-sulfonamide is reacted with an alkoxycarbonylating agent, an isocyanate compound or an acylating agent in the presence of an amine. 2-sulfonamide-amine adduct. (X is an acyl group, alkoxycarbonyl group or aminocarbonyl group; amine is a tertiary amine, secondary amine, primary amine or pyridines; n is 1 or 2) [Selection] None |
priorityDate | 2014-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 211.