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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04
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filingDate 2015-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e16e59d9ccb5b759c384fd520345f17
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publicationDate 2015-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015199705-A
titleOfInvention Method for synthesizing psoralen derivatives
abstract [Problem] To provide a production method capable of obtaining a high-purity psoralen derivative in a good yield and easily industrialized. As shown in FIG. 1, a compound represented by the formula (II) is acetylated with, for example, 2-chloroacetyl chloride, etc., and led to a compound of the formula (III), and represented by the formula (III). The compound is subjected to Fries rearrangement leading to a compound of formula (IV). A process for producing the compound represented by the formula (IV) by cyclization, reduction and aromatization to lead to the compound represented by the formula (I). In the formula, R 1 is H or a linear / branched C 1 - alkyl group of 6; R 2 is H or a linear / branched C 1 - 6 alkyl group or a linear / branched Jo of C 1 - a 6 alkoxy group. [Selection] Figure 1
priorityDate 2014-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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