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filingDate 2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39cd26cfc18c108b9008f8ecc1592ad0
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publicationDate 2015-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015193614-A
titleOfInvention Granular pharmaceutical composition
abstract Disclosed is a granular pharmaceutical composition containing bixalomer having low moldability at a high blending ratio, reducing the proportion of fine powder (particles less than 500 μm) and having appropriate strength. 500 μm produced by extrusion granulation containing about 50 to about 99% by weight of bixalomer and hypromellose having a viscosity of about 6 mPa · s in a 2% aqueous solution at 20 ° C., based on the weight of the pharmaceutical composition. A granular pharmaceutical composition which is a granule, powder or fine granule having a proportion of less than about 25% by weight of particles and a breaking load of about 5 to about 100 N. [Selection figure] None
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