| abstract |
A pharmaceutical composition comprising coenzyme Q10 (CoQ10) and angiogenesis that treats cancer, selectively reduces cancer cell proliferation, causes apoptosis in cancer cells, and is mediated by tumors A method of using CoQ10 to inhibit the activity is provided. Topical formulations of CoQ10 reduce the growth rate of tumors in animal subjects. Experiments described herein have shown that CoQ10 increases the rate of apoptosis in skin cancer cell cultures but not normal cells. Furthermore, treatment of tumor-bearing animals with a topical formulation of CoQ10 has been shown to dramatically reduce the rate of tumor growth in the animals. [Selection] Figure 1 |