| abstract |
Modification of glycosylation of a polypeptide to modify its biological properties. A technique for glycosylation, more specifically, resistant to enzymatic degradation, thereby modulating one or more of its biological properties or the properties of a therapeutic moiety incorporated therein. Techniques for producing glycosylated structures that react, in particular, one or more covalent linkages between a sugar acceptor and a sialic acid compound by reacting an activated carbohydrate substrate containing fluorine, such as a 3-fluorosialic acid compound, with a sugar acceptor A method for producing a sex conjugate is provided. [Selection figure] None |