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filingDate 2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c6b14baa394dd4eaf04c2eff865cb9
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publicationDate 2015-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015180707-A
titleOfInvention Dimensional analysis of conjugated sugars by GPC and SEC-MALS
abstract PROBLEM TO BE SOLVED: To provide a new and improved method for measuring molecular size, molecular weight and related parameters for conjugated saccharide antigens, particularly for meningococcal saccharide conjugates. Using GPC (Gel Permeation Chromatography) and Size Removal Chromatography with detection by multiple angle light scattering photometry (SEC-MALS), each of the molecular size and molecular weight of a sugar conjugate is accurately measured. Can do. The invention includes (a) a process for measuring the molecular size of a conjugated saccharide antigen in a sample, comprising the step of analyzing the sample by GPC, and (b) conjugation in the sample. A process for measuring the molecular weight of a saccharide antigen, comprising analyzing a sample by SEC-MALS is provided. [Selection figure] None
priorityDate 2004-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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