| abstract |
A method for producing a vitamin K-dependent protein using in vitro host cells. A method for producing a vitamin K-dependent protein using a host cell into which a vitamin K-dependent protein-encoding nucleic acid, a vitamin K-dependent carboxylase-encoding nucleic acid, and a vitamin K epoxide reductase-encoding nucleic acid are introduced. The method wherein the vitamin K-dependent protein is coagulation factor Factor VIII, Factor IX, Factor X, prothrombin, protein C, and protein S. [Selection figure] None |