Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e66dcd041b390d50bd6668a9009a1e6f |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
2014-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92036234bd2f30c8219dafb10764f53f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ee58dc75e0f55a2ef1a16e70384f6cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ae368dff7404a8934a2cdf0b5fe044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3cd15385305ef5cdc2e10af6adb4a86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce2a3021bd96c12f763c47b3cce4d4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae12b53a97eb19bfd5135698eeb940b5 |
publicationDate |
2015-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2015163050-A |
titleOfInvention |
Thermostable acyl CoA synthetase and method for producing the same |
abstract |
An object of the present invention is to provide an acyl-CoA synthetase that has excellent stability and exhibits sufficient activity even at a temperature (30 to 37 ° C.) commonly used in clinical tests, by a genetic engineering technique. . By replacing a specific amino acid residue with another amino acid residue in the amino acid sequence of acyl CoA synthetase derived from Pseudomonas fragii, it has thermal stability while having activity at room temperature (30 to 37 ° C.). And the stability in solution can be dramatically improved. [Selection figure] None |
priorityDate |
2014-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |