abstract |
The present invention relates to four polypeptides called PRT5, PRT6, PRT7 and PRT8, nucleic acids encoding them, compositions containing these proteins, and therapeutic and diagnostic uses of antibodies that specifically recognize these polypeptides. Offer. Four polypeptides called PRT5, PRT6, PRT7 and PRT8, which are chemokine-like secreted proteins, characterized by PRT5 and PRT8 in glucose metabolism and PRT6 in androgen regulation However, PRT7 is correlated with cancer, and each of these proteins is used to treat disorders selected from diabetes, metabolic syndrome, obesity, endocrine diseases and muscle disorders. [Selection figure] None |