| abstract |
The present invention selectively regulates the activity of HPTPβ, thereby enhancing angiogenesis signaling, stimulating angiogenesis (angiogenesis), and / or increasing blood flow in ischemic tissue, or angiogenesis. To develop antibodies, eg, humanized monoclonal antibodies, that reduce signaling, reduce blood vessel growth, and / or reduce blood flow to the affected tissue. The present invention relates to an antibody that binds to human protein tyrosine phosphatase β (HPTPβ), an antigen-binding fragment thereof, and uses thereof. [Selection] Figure 1 |