| abstract |
To provide a basal insulin analogue that is more hydrophilic than human insulin and can be administered orally or by pulmonary rather than subcutaneously as an insulin preparation that improves treatment of diabetes mellitus and improves quality of life. Protease-stabilized insulin by acylation in which an acyl moiety is bound to a lysine residue at position B29 of human insulin A14E, B25H, desB30 human insulin. [Selection] Figure 1 |