| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7de02e4b28736bfb52de8bb358be203e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2884 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate |
2015-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b679deab699bfaa79f2dd3a250405d60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b3e60959988abac77a81ff0cdfa5a45 |
| publicationDate |
2015-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2015155409-A |
| titleOfInvention |
Monoclonal antibody against CD44 used for the treatment of squamous cell carcinoma of the head and neck |
| abstract |
The present invention provides a novel method and means for preventing, treating, or diagnosing head and neck squamous cell carcinoma (HNSCC) using an anti-CD44 antibody. A pharmaceutical comprising a humanized monoclonal anti-CD44 antibody, or an antigen-binding fragment thereof. Wherein the HNSCC is characterized by the expression of CD44, the monoclonal antibody comprising a VH domain having an amino acid sequence that is at least 85% identical to a VH domain having a specific sequence of amino acids, and an amino acid sequence of the specific sequence Comprising a VL domain having an amino acid sequence that is at least 85% identical to a VL domain having a humanized antibody with an antibody produced by a hybridoma deposited at ATCC under accession number PAT-4621 and to CD44 A drug that competes for binding. [Selection figure] None |
| priorityDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |