| abstract |
The present invention provides processes and intermediates useful in the preparation of S1P1 receptor modulators. The present invention underlies S1P1 receptor-related disorders (eg, lymphocyte-mediated diseases and disorders, transplant rejection, autoimmune diseases and disorders, inflammatory diseases and disorders, cancer, and vascular integrity. (R) -2- (Formula (Ia), a S1P1 receptor modulator, useful in the treatment of conditions characterized by a defect or associated with angiogenesis as may be pathological) Processes and intermediates useful in the preparation of 7- (4-cyclopentyl-3- (trifluoromethyl) benzyloxy) -1,2,3,4-tetrahydrocyclopenta [b] indol-3-yl) acetic acid and its salts About the body. [Selection figure] None |