abstract |
Disclosed is an in situ forming depot pharmaceutical preparation with improved tolerability, acute toxicity and storage stability characteristics. A biodegradable polymer, a poly (ethylene) glycol having a molecular weight of 450 <Mw <650 Da, a chemically inert end group, and a freezing point at a temperature of 8 to 20 ° C., pharmaceutical In-situ forming depot formulation comprising an pharmaceutically active substance, optionally additives and less than 0.5% biologically acceptable organic solvent. [Selection figure] None |