| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_424db9d56b06a23aed410fcf5df652f3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2301-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B11-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-201
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B11-193
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate |
2014-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07b9aab11cab06061329bb5eee41c339
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87351f5ea46757d351b4df37bdfef12f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a26892c660095679b7b500799dcbf6b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c4c79b81fe103c00cd38c012f7c8ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c90f74eec6c83605063d038bee58d7 |
| publicationDate |
2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2015127316-A |
| titleOfInvention |
Composition for hot melt extrusion and method for producing hot melt extruded product using the same |
| abstract |
The object of the present invention is to provide a heat-melt-extruded product by a method simpler than a heat-melt extrusion composition and a spray-drying method, in which there is no inactivation of the drug due to heat or the like by heat-melt extrusion at a lower temperature than before. A method for producing an extruded product is provided. A composition for hot melt extrusion comprising at least a hypromellose acetate succinate (HPMCAS) having a molar substitution degree of hydroxypropoxy group of 0.40 or more and a drug is provided. In addition, a composition for heating and melt extrusion containing at least a hypromellose acetate succinate having a hydroxypropoxy group molar substitution degree of 0.40 or more and a drug is obtained at a temperature higher than the melting temperature of the hypromellose acetate succinate or a hypromellose acetate succinate. Provided is a method for producing a heated melt extrudate, comprising at least a step of heat melting at a heat melting temperature equal to or higher than a temperature at which both an acid ester and a drug are melted, and extruding. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016098179-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018525482-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018172371-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3381447-A1 |
| priorityDate |
2013-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |