http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015123004-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40b609c33009f7c78d93591cb8ad181a
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
filingDate 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78dee61432e5ad4026824877c73db888
publicationDate 2015-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2015123004-A
titleOfInvention Cell lines derived from central nervous system neurons and methods for establishing them
abstract A neuronal cell line derived from the central nervous system and a method for establishing the same are provided. At least one gene selected from the group consisting of Rb gene, p107 gene, and p130 gene has a lox sequence inserted upstream and downstream, and a lox sequence inserted upstream and downstream. A step of introducing a vector containing a NeuroD1 gene promoter region and a Cre gene downstream thereof into a central nervous system progenitor cell of an animal having a genotype in which a gene that has not been deleted; a cell into which the vector has been introduced And a step of recovering a cell having a genotype from which Rb gene, p107 gene, and p130 gene are deleted, among the cultured cells, cells derived from central nervous system neurons A strain establishment method and a cell strain derived from a central nervous system neuron established by this method. [Selection figure] None
priorityDate 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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