http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015123004-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40b609c33009f7c78d93591cb8ad181a |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78dee61432e5ad4026824877c73db888 |
publicationDate | 2015-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2015123004-A |
titleOfInvention | Cell lines derived from central nervous system neurons and methods for establishing them |
abstract | A neuronal cell line derived from the central nervous system and a method for establishing the same are provided. At least one gene selected from the group consisting of Rb gene, p107 gene, and p130 gene has a lox sequence inserted upstream and downstream, and a lox sequence inserted upstream and downstream. A step of introducing a vector containing a NeuroD1 gene promoter region and a Cre gene downstream thereof into a central nervous system progenitor cell of an animal having a genotype in which a gene that has not been deleted; a cell into which the vector has been introduced And a step of recovering a cell having a genotype from which Rb gene, p107 gene, and p130 gene are deleted, among the cultured cells, cells derived from central nervous system neurons A strain establishment method and a cell strain derived from a central nervous system neuron established by this method. [Selection figure] None |
priorityDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.