| abstract |
Disclosed is a topical composition for treating symptoms of reduced skin elasticity, i.e. for treating, reversing and / or preventing signs of skin aging, including fine lines and wrinkles on the skin. A composition comprising DL-desthiobiotin or a locally applicable salt or prodrug thereof as an active ingredient. The composition is applied topically to the skin and has the effect of promoting lysyl oxidase-like 1 (LOXL-1) activity, thus improving elastin remodeling, fine lines, wrinkles, skin sagging, And other symptoms caused by reduced elastin function. [Selection figure] None |