| abstract |
Provided is a novel cell-binding agent-drug conjugate having water solubility. A conjugate represented by the following formula (II): (CB is a cell binding agent; D is a drug linked via a disulfide or the like; R1 to R10 are the same or different, H, C1-6 linear alkyl, or a charged substituent such as SO3-, PO32-, trimethylammonium, etc. L, m and n are integers of 0 to 4; A is absent or a polyoxyethylene group; Y is carbonyl, etc .; q is an integer of 1 to 20). |