| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_424db9d56b06a23aed410fcf5df652f3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1694
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 |
| filingDate |
2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec3000864c6202eb7c41102c81ceeec2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c90f74eec6c83605063d038bee58d7 |
| publicationDate |
2015-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2015117240-A |
| titleOfInvention |
Composite granulated product, immediate-release tablet and production method thereof |
| abstract |
Disclosed is an immediate-release tablet having excellent binding and disintegrating properties and excellent storage stability. A composite granulated product comprising at least a low-substituted hydroxypropyl cellulose having a hydroxypropoxy group substitution degree of 5 to 16% by mass and D-mannitol, which is contained in the D-mannitol. A composite granulated product having a D-sorbitol content of 0.9% by mass or less, an immediate release tablet containing at least this composite granulated product and a drug, and a hydroxypropoxy group substitution degree of 5 to 16% by mass A step of obtaining a water dispersion by blending substituted hydroxypropylcellulose, first D-mannitol and water, and adding the obtained water dispersion to the second D-mannitol for granulation A granulated product comprising at least a granulating step, wherein the total content of D-sorbitol contained in the first and second D-mannitols is 0.9% by mass or more. Production process or the like of the composite granules is provided at. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6822619-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020204142-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021205886-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016098459-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016098459-A1 |
| priorityDate |
2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |