| abstract |
A lentiviral vector is provided. The lentiviral vector comprises a 5 ′ long terminal repeat (LTR) and a 3 ′ LTR; a first nucleic acid sequence operably linked to the 5 ′ LTR; a functional REV coding sequence and rev. A second nucleic acid sequence operably linked to the 5 ′ LTR, comprising a response element (RRE) containing sequence, wherein the RRE containing sequence is located upstream of the REV coding sequence, Wherein the transcription of the first nucleic acid sequence and the second nucleic acid sequence is driven by the 5 ′ LTR. [Selection figure] None |