abstract |
Several novel and, such as binding with high specificity to pancreatic cancer and other cancers, not to normal or benign pancreatic tissue, binding to a high percentage of early pancreatic cancer, etc. Providing compositions and methods of use of anti-pancreatic cancer antibodies or fragments thereof, such as murine, chimeric, humanized, or human PAM4 antibodies that exhibit useful therapeutic properties. An antibody such as PAM4 antibodies, CA19.9, compared with DUPAN2, SPAN1, Nd2, B72.3, and Le a antibodies and Le (y) Other known antibodies such as antibodies that bind to the Lewis antigen A composition for the treatment of cancer, such as pancreatic cancer, which binds to a PAM4 antigen exhibiting a unique cellular and tissue distribution. [Selection figure] None |