| abstract |
Disclosed are compositions and methods comprising glycyl-tRNA synthetase having non-canonical biological activity. Isolated glycyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activity, and related compositions and methods are provided. In certain embodiments, the non-canonical biological activity exhibited by the GlyRS polypeptides of the invention includes, but is not limited to, regulation of cell proliferation, regulation of apoptosis, regulation of cell migration, cell signaling And / or regulation of cytokine production and / or secretion. [Selection] Figure 2 |