Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93e07779b091b1e947bfb639c996e751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97abb9a6c9901a59855c35cd53ec9d10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_809012cb820bf51b5cd5b5a5ea9217fc |
publicationDate |
2015-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2015096502-A |
titleOfInvention |
Compositions and methods for inhibiting tumor progression |
abstract |
Compositions and methods for classification, diagnosis, treatment and prevention of tumors characterized by expression of β2 encoded by the SCN2B gene and / or activation of Notch due to loss of REST function. Monoclonal antibodies that bind to β2 and block β2 binding to Notch1, which regulate cellular processes such as epithelial-mesenchymal transition (EMT), cell migration and apoptosis. [Selection] Figure 8 |
priorityDate |
2007-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |