| abstract |
Disclosed is a compound that modulates pyruvate kinase M2 (PKM2). A composition comprising a compound that modulates pyruvate kinase M2 (PKM2) is described herein. Also described herein are methods of using compounds that modulate PKM2 in the treatment of cancer. The invention also includes compositions and pharmaceutical kits comprising the compounds of the invention, and pyruvate kinase function (eg, including cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia (BPH), eg, The use of such compositions and kits in methods of treating diseases and conditions associated with (PKM2 function) is provided. [Selection figure] None |