| abstract |
【Task】 An object of the present invention is to obtain a preparation having high transdermal absorbability. [Solution] As a result of intensive studies by the present inventors, it was found that an external preparation for skin containing a water-soluble active ingredient, formula (1), mucopolysaccharide, and collagen solves this problem. (A is an alkylene group having 2 to 5 carbon atoms, R and R 'are carbon 10 to 30, m is 5 to 100, n is 1 to 10, p is 5 to 500, q is 1 to 8) Furthermore, when an oil phase containing at least one selected from sugar ceramide and a polyhydric alcohol emulsified with a polyhydric alcohol containing 50% by weight or more of glycerin are blended, the oil-soluble component is also highly safe. it can. [Selection figure] None |