| abstract |
Disclosed are a potent and safe new adjuvant and immunogenic composition and vaccine for enhancing innate immunity and enhancing the efficacy of the vaccine. It contains at least one lipoprotein, such as a Lip protein, Lip fragment or Lip variant, which may be isolated from various strains of bacteria including but not limited to Neisseria meningitidis An adjuvant, wherein the lipoprotein comprises at least one pentamer unit and at least one lipid moiety, wherein the lipoprotein constitutes at least 10% of the adjuvant by weight / volume ratio. [Selection] Figure 1 |