| abstract |
The present invention relates to a method for producing a multivalent binding peptide including a bispecific binding peptide having an immunoglobulin effector function, and to treat or prevent a disease, disorder or condition using the peptide, and to improve at least one symptom. Providing a method. From the amino terminus to the carboxy terminus, a first binding domain comprising immunoglobulin light and heavy chain variable regions, an immunoglobulin-derived constant subregion comprising a hinge or hinge-like domain, type II C A single chain multispecific binding protein comprising a linker peptide comprising an amino acid sequence derived from a stalk region of a lectin protein and a second binding domain comprising immunoglobulin light and heavy chain variable regions. [Selection] Figure 1 |