| abstract |
A Trk kinase inhibitor is provided. Compounds of formula (I) and salts thereof, wherein R 1 , R 2 , R 3 , R 4 , X, Y, and n have the meanings defined herein, are inhibitors of Trk kinases. Yes, it is useful for the treatment of diseases such as pain, cancer, inflammation, neurodegenerative diseases, and certain infectious diseases that can be treated with Trk kinase inhibitors. For example, a pharmaceutical composition comprising a compound of the invention, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable diluent or carrier is also provided. [Selection figure] None |