| abstract |
Disclosed is a novel compound having selective breton-type tyrosine kinase inhibitory activity, excellent metabolic stability, low hepatotoxicity, and can be a safe therapeutic agent for diseases involving B cells and mast cells. 6-Amino-9-[(3R) -1- (2-butynoyl) -3-pyrrolidinyl] -7- (4-phenoxyphenyl) -7,9-dihydro-8H represented by the following formula: -Purin-8-one or a salt thereof. [Selection figure] None |