| abstract |
Formula (I) [Where: A represents 5- to 12-membered aryl or 5- to 12-membered heteroaryl, each of which may be unsubstituted or substituted; Y is a single bond,-(CH 2 ) p- , -X-, -CH 2 -X- or -X-CH 2- ; ・ X is -O-,-S-,-N (R 2 )-,> C = O,> S (= O),> S (= O) 2, -OC (= O)-,-C (= O) -O -, - N (R 2) -C (= O) - or -C (= O) -N (R 2) - a and; Each L is independently a single bond, C 1-3 alkylene, C 2-3 alkenylene or C 2-3 alkynylene; R 1 is C 1-6 alkyl, C 2-6 alkenyl or C 2-6 alkynyl, each of which may be unsubstituted or substituted; Each Z is independently -N (R 2 ) 2 , -OR 2 , -SR 2 , -S (= O) R 2 or -S (= O) 2 R 2 ; Each R 2 is independently hydrogen, C 1-6 alkyl, C 2-6 alkenyl or C 2-6 alkynyl, and the alkyl, alkenyl and alkynyl groups may be unsubstituted or substituted; May be; M is 0, 1, 2 or 3; N is 1, 2 or 3; • p is 1, 2 or 3. ] The benzimidazoles and their pharmaceutically acceptable salts are RSV inhibitors and can therefore be used for the treatment or prevention of RSV infection. [Selection figure] None |