http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014533241-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2012-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014533241-A |
| titleOfInvention | Ultra-concentrated fast-acting insulin analogue preparation |
| abstract | A pharmaceutical formulation has a mutant insulin B-chain polypeptide comprising ortho-monofluoro-phenylalanine at position B24 in combination with an amino acid substitution containing an acidic side chain at position B10, wherein the insulin is 0.6 mM. It can be present at a concentration of ~ 3.0 mM. The formulation may optionally be free of zinc. In addition, one or more amino acid substitutions may be present at positions B3, B28, and B29. The mutant B chain polypeptide may be part of a proinsulin analog or a short chain insulin analog. The insulin analog can also be an analog of mammalian insulin such as human insulin. A method for reducing a patient's blood glucose level comprises administering to the patient a physiologically effective amount of the insulin analog or a physiologically acceptable salt thereof. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016506366-A |
| priorityDate | 2011-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 339.