abstract |
The present specification relates to lowering serum uric acid levels in a subject and to increasing serum uric acid levels, characterized by administering a composition comprising a first uric acid lowering drug and a second uric acid lowering drug Disclosed are pharmaceutical compositions, methods and kits for treating disorders. In one embodiment, the first uric acid lowering drug is (−)-halofenate, (−)-halofenic acid or a pharmaceutically acceptable salt thereof. In one embodiment, the second uric acid lowering drug is a uric acid production inhibitor, a uric acid excretion drug, uricase or a pharmaceutically acceptable salt thereof. |