| abstract |
Shown herein are compounds and methods for their synthesis. The compounds presented herein are useful for the treatment, prevention and / or management of various disorders (eg, pain, neurological disorders, psychiatric disorders and neuromuscular disorders). The compounds shown herein modulate the activity of opioid receptors (eg, μ-opioid receptors) in the central or peripheral nervous system. Also provided herein are pharmaceutical compositions containing the above compounds and methods for their use. |