abstract |
The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinases such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The present invention relates to pharmaceutically acceptable compositions comprising the compounds of the present invention, methods of treating various diseases, disorders and conditions using the compounds of the present invention, processes for preparing the compounds of the present invention, the present It relates to intermediates for the preparation of the compounds of the invention as well as solid forms of the compounds of the invention. The compounds of the invention have the formula I or II, wherein the variables are as defined herein. |